Women of child-bearing age must be supplied with K-negative blood.
Patients with red cell alloantibodies:
Blood that is negative for the antigen against which the alloantibody is detected.
Give K negative blood insofar as possible as it can be difficult to exclude anti-K antibodies in the presence of other alloantibodies.
Patients with anti-D who have a rr phenotype should receive rr, K-negative blood.
Patients with Rh antibodies should be provided with Rh-matched blood to prevent further alloimmunisation.
Patients with alloantibodies against low-frequency antigens can be issued with IAT-compatible blood, rather than selecting antigen-negative units, which may be difficult to find.
Patients with clinically-insignificant alloantibodies can be supplied with 37°C IAT-compatible blood.
Children >1 year-old may use standard adult red cell components.
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