Components sourced from donors with at least one previous transfusion in the last two years, and negative for all mandatory microbial investigations (to reduce risk of infection).
All components should be free of clinically-significant antibodies, including high-titre anti-A and anti-B (to reduce the risk of RBC haemolysis).
ABO/RhD group compatible with both mother and infant (unless local policy specifies group O).
Negative for any antigens against which maternal alloantibodies are directed.
In SAGM additive solution.
Less than 5 days old.
HbS negative (sickle screen negative).
K-negative (unless the maternal alloantibody is anti-k, in which case k-negative blood should be given).
Hct 0.5-0.7.
CMV seronegative.
Irradiation is only necessary if the neonate received IUT.
If irradiated, the shelf-life is 24hours post-irradiation.
A serological crossmatch is not required if the neonatal DAT is negative and there are no clinically-significant maternal alloantibodies. In such cases, ABO/RhD compatible blood can be issued without a crossmatch.
IAT crossmatch-compatible against maternal plasma (or, if unavailable, neonatal plasma) if there are clinically-significant maternal alloantibodies. IAT crossmatch must be done until the neonatal DAT is negative.
Approximate volume 295ml.
Adult emergency O- blood isnot suitable for neonatal transfusion. It lacks the additional component safety specification.
Leave A Comment