Schistocytes (RBC fragments) are fragmented red cells resulting from shear stress (mechanical damage).

Causes:

Schistocyte. Peripheral blood film from a patient with microangiopathic haemolytic anaemia, showing a schistocyte (fragmented red blood cell).
Peripheral blood film from a patient with microangiopathic haemolytic anaemia, showing a schistocyte (fragmented red blood cell).